USB I/O module suddenly not responding to M64/65 commands

It’s getting power and has worked great for years. I’m running Mach 3 but after installing Windows 7 up from Windows NT I can’t get the module to work. I get the error message “Waiting for I/O board to connect” in Mach. Everything else is working fine.

I’ve tried reinstalling the driver, checked cables, unplug and replug…

Any thoughts?